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It’s no secret that men begin to slowly lose their
testosterone after the age of 30, which oftentimes leads to a decrease in
muscle mass and libido. Fewer men know, however, that the age-related decline
in our testosterone levels is also associated with a decrease in our cognitive
abilities and even dementia.
Previous research conducted with animals indicates that testosterone replacement therapy leads
to an improvement in cognition and reduces the risk of Alzheimer's disease
pathology in the brain. But now, a new placebo-controlled study conducted on older
men with low testosterone levels and self-reported memory complaints has
confirmed certain positive effects of testosterone supplementation on human
cognitive functioning.
For their research, scientists evaluated the baseline
cognitive performance of 44 men and divided them in two groups. The first group
(A) was administered 24 weeks of testosterone replacement therapy followed by a
four-week break (washout), and then another 24 weeks of placebo. The second
group (B) received the same treatment, but in reverse order: placebo, break,
testosterone treatment.
After re-evaluating the participant’s cognitive functioning after the
treatment, researchers identified a small but consistent improvement in Group
A’s mental performance, which was sustained throughout the washout and placebo
periods. Group B, saw and even greater increase in cognitive functioning
following testosterone treatment and “a trend towards an increase when compared
to placebo treatment.”
Although larger scale studies with a longer follow-up are
needed for a more conclusive determination, this study indicates a clear
positive effect of testosterone treatment on cognitive function in older men.
Testosterone plays a major part in the overall functioning
of our bodies, and it is very important to track your testosterone levels,
especially at an older age. If you suspect that your hormonal health might be
out of balance, consult a qualified professional
as soon as possible.